报告题目：Human papillomavirus vaccination strategy: Modelling and implications

报告人：高莎莎（美国佛罗里达大学在读博士）

报告时间：2021年10月24日上午9:00—9:40

报告地点：复杂系统研究所（腾讯会议）

报告人简介：高莎莎，美国佛罗里达大学在读博士，研究方向为生物数学、传染病动力学等。曾荣获 Eleanor Award（颁发给有研究潜能的女研究生）、Teaching Award、优秀毕业生、优秀硕士毕业论文等。在 Bulletin of Mathematical Biology 等杂志发表SCI论文4篇，一篇SCI已接受，两篇已投出。在传染病动力学研究领域成绩显著，现担任美国 Journal of Biological Dynamics 等3个SCI杂志的评论员。

报告摘要：Vaccination is effective in preventing HPV infection. How to choose the target population for vaccination and what’s the best distribution strategy need to be further investigated. In this paper, we use a dynamic model to assess HPV vaccination strategies in a heterosexual population combined with men who have sex with men (MSM). The basic reproduction numbers are obtained. From the analysis and numerical investigations, we have several conclusions.(1) To eliminate HPV infection, the priority of vaccination should be given to MSM, especially in countries that have already achieved high coverage in females. The heterosexual population gets great benefit but MSM only get minor benefit from vaccinating heterosexual females or males. (2) The best vaccination strategy is to vaccinate MSM firstly as many as possible, then heterosexual females, lastly heterosexual males. (3) Given a fixed vaccination coverage of MSM, distributing the remaining vaccines to only heterosexual females or males leads to a similar prevalence in the total population. This prevalence is lower than that when vaccines are distributed to both genders. The evener the distribution, the higher the prevalence in the total population. (4) Vaccination becomes less cost-effective as more vaccines are given. It is more effective to allocate vaccines to a region with lower vaccination coverage.